Venlafaxine price at Cost Plus Drugs

The cash price for Venlafaxine at Mark Cuban Cost Plus Drug Company, PBC, without insurance, for each strength they sell. Then see how it compares with what 2027 Medicare plans near you would charge.

Venlafaxine at Cost Plus Drugs

  • Venlafaxine 25mg Tablet
    $5.86 for 30 · $7.57 for 90 + $5.25 shipping per orderAbout $51 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine 37.5mg Tablet
    $5.91 for 30 · $7.72 for 90 + $5.25 shipping per orderAbout $52 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine HCl ER 37.5mg Extended Release Capsule
    $6.09 for 30 · $8.26 for 90 + $5.25 shipping per orderAbout $54 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine HCl ER 37.5mg Tablet Extended Release
    $8.77 for 30 · $16.32 for 90 + $5.25 shipping per orderAbout $86 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine 50mg Tablet
    $6.04 for 30 · $8.12 for 90 + $5.25 shipping per orderAbout $53 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine 75mg Tablet
    $6.96 for 30 · $10.89 for 90 + $5.25 shipping per orderAbout $65 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine HCl ER 75mg Extended Release Capsule
    $6.01 for 30 · $8.02 for 90 + $5.25 shipping per orderAbout $53 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine HCl ER 75mg Tablet Extended Release
    $6.91 for 30 · $10.73 for 90 + $5.25 shipping per orderAbout $64 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine 100mg Tablet
    $6.36 for 30 · $9.09 for 90 + $5.25 shipping per orderAbout $57 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine HCl ER 150mg Extended Release Capsule
    $6.89 for 30 · $10.66 for 90 + $5.25 shipping per orderAbout $64 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine HCl ER 150mg Tablet Extended Release
    $8.59 for 30 · $15.76 for 90 + $5.25 shipping per orderAbout $84 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗
  • Venlafaxine HCl ER 225mg Tablet Extended Release
    $13.05 for 30 · $29.15 for 90 + $5.25 shipping per orderAbout $138 a year, one a day, on 90-day orders
    See this at Cost Plus Drugs ↗

Cost Plus Drugs' posted cash prices as of October 26, 2026, including their pharmacy fee. Prices can change; Cost Plus Drugs' website shows the current price. Yearly figures are estimates.

Medicare drug coverage for Venlafaxine in 2027

On 286 of 286 2027 Medicare drug lists (100%), most often on tier 2.

Some plans list it with quantity limits.

Each Medicare drug plan, and each Medicare Advantage plan with drug coverage, uses a drug list (formulary) that CMS publishes. Being on a plan's list means the plan covers the drug; what you pay depends on the plan's tier, deductible and pharmacy. Counts are from CMS's 2027 formulary files.

Compare with Medicare plans near you

Whether Cost Plus Drugs is lower than a Medicare plan depends on the plan, your other prescriptions and your pharmacy. Enter your ZIP code on the next page to see each 2027 plan's estimated yearly cost for Venlafaxine, next to the Cost Plus price.

Compare with 2027 Medicare plans

About Venlafaxine at Cost Plus Drugs

  • Drug group: Other antidepressants
  • Brand-name version: Effexor, Effexor XR. The prices above are for the generic unless a brand name is shown next to the strength.
  • Forms sold at Cost Plus Drugs: tablet, extended release capsule, tablet extended release
  • Shipping: $5.25 per order, mailed to you. A prescription is required.
  • Insurance: these are cash prices. Bought this way, outside your insurance, a drug generally doesn't count toward a Medicare plan's deductible or yearly out-of-pocket cap.

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